Sekhar Pothireddy
Professor
Research Interests
Our lab research is currently focused on elucidating the mechanisms underlying acute lung injury, bronchopulmonary dysplasia, and lung cancer. We are currently utilizing cell culture and genetically engineered mouse models as well as clinical samples to define the role of alveolar epithelial stress signaling in acute lung injury and repair, and pathogenesis. We are targeting Nrf2 and of AP-1 signaling to improve the regeneration of alveolar epithelium following lung injury in preclinical models. In addition, we are also examining the role of AP-1 family of proteins in the lung cancer development and progression using preclinical models.
At a Glance
- Title Professor
- College College of Medicine at Chicago - Clinical Sciences
- Department Department of Pediatrics
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