Monica Lee
Assistant Professor
Research Interests
Endothelial cell (EC) health is largely determined by the regulation of transcription factors that control the transcriptome and identity of ECs. These transcriptional regulators rely on nucleocytoplasmic shuttling, where the control of transcription factor subcellular localization is essential for EC health. The controlled exchange of molecules between the nucleus and cytoplasm occurs through nuclear pore complexes, one of the largest components of the nuclear envelope. In the Lee Lab, we study the contribution of nuclear pore proteins (i.e. nucleoporins) in vascular health and disease. The Lee Lab utilizes a combination of high-content screening together with modern in vitro and in vivo techniques to allow for a multi-tier, integrative approach toward translational research.
At a Glance
- Title Assistant Professor
- College College of Medicine at Chicago - Basic Sciences
- Department Department of Physiology and Biophysics
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