Kiwook Kim
Assistant Professor
Research Interests
- Macrophages have been known as an innate myeloid cell populations. As one of immune cell populations, macrophages engulf and digest the non-self materials (e.g. pathogenic-bacteria, virus etc.) This process is called 'phagocytosis'. Once they phagocytose pathogens, macrophages orchestrate the inflammation by secreting inflammatory cytokines (TNF-a, IL1b, IL6) and anti-inflammatory cytokines (TGF-b, IL10) dependent on the tissue context. Besides these immune functions, macrophages contribute to the tissue-homeostasis by expressing tissue-specific gene expressions. Our group focuses how tissue-resident macrophages obtain tissue-specific gene expression profiles and tissue-specific functions.
- We are studying the macrophage-mediated inflammation and tissue repair in lung, peritoneum and gut mesentery.
- - The role of lung macrophages in acute lung inflammation
- - The role of peritoneal macrophages and mesenteric macrophages in gut inflammation
At a Glance
- Title Assistant Professor
- College College of Medicine at Chicago - Basic Sciences
- Department Department of Pharmacology and Regenerative Medicine
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