Amelia M. Bartholomew

This laboratory is focused on organ and tissue regeneration using mesenchymal stem cells. Mesenchymal stem cells (MSC)are rare residents of the bone marrow and other tissues which can give rise to a number of tissue types. More importantly, they have powerful regulatory properties and can direct cells to sites of injury for accelerated healing. We have three main lines of investigation: 1) the use of MSC on scaffolds to speed wound healing, 2) the use of MSC administered to modify the immune response to the transplanted organ to reduce or completely eliminate the need for anti-rejection drugs, and 3) the use of stem cell mixtures to regenerate kidney tissue.