Jose Cordoba-Chacon

    Email Address:
    College: Medicine Department: Division of Endocrinology, Diabetes and Metabolism; Department of Medicine
    Title: Instructor
    Office: CMWT #816 Phone: 3123553565
    Participating in the Chancellor’s Undergraduate Research Awards program: Yes

    Research Interest:
    Overall research interests: Lipid homeostasis; Non-alcoholic fatty liver disease (NAFLD); Non-alcoholic steatohepatitis (NASH); Diabetes; Nutrition

    My specific research interests are focused on the role that hepatocyte PPARgamma plays in the development of hepatic liver disease and how hepatocyte PPARgamma regulates postprandial dyslipidemia.

    We use tissue-specific knockout mouse models to perform experiments in live animals to assess physiological processes: diet-induced obesity, diet-induced steatosis and NASH, glucose and insulin tolerance tests, bleedding in different metabolic conditions to measure metabolic endpoints, etc. In addition, we use a wide spectrum of molecular biology techniques to address our hypothesis in samples derived from in vivo studies: qRT-PCR, western-blots, GC/MS, LC/MS, etc.

    Minimum time commitment in hours per week: 10

    Qualifications of a Student:
    Excellent Qualifications. Biological Sciences Background. Basic understanding of animal physiology.

    Brief Summary of what is expected from the student:
    Motivated students. Commitment with research project. Follow-up discussions and understanding of the research.

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