Amelia M. Bartholomew

    Email Address:
    College: Medicine Department: Surgery
    Secondary Department: Bioengineering
    Title: Professor and Chief, Translational Research
    Office: 5113 COMRB Phone: 355-4065
    Participating in the Chancellor’s Undergraduate Research Awards program: Yes

    Research Interest:
    This laboratory is focused on organ and tissue regeneration using mesenchymal stem cells. Mesenchymal stem cells (MSC)are rare residents of the bone marrow and other tissues which can give rise to a number of tissue types. More importantly, they have powerful regulatory properties and can direct cells to sites of injury for accelerated healing. We have three main lines of investigation: 1) the use of MSC on scaffolds to speed wound healing, 2) the use of MSC administered to modify the immune response to the transplanted organ to reduce or completely eliminate the need for anti-rejection drugs, and 3) the use of stem cell mixtures to regenerate kidney tissue.

    Minimum time commitment in hours per week: 10

    Qualifications of a Student:
    Students interested in this type of inquiry should be highly motivated with the ability to attend to fine details. They should come prepared with the anticipation that the first few weeks will be devoted to reading literature so that they may become familiar with sufficient background science to meaningfully participate in the lab. A GPA of 3.75 or higher is required. This opportunity will be limited to first or second year students with the anticipation that it will be a 3-4 year commitment.

    Brief Summary of what is expected from the student:
    The student is expected to attend the weekly research meetings, participate in journal club, and gain the necesssary skills to significantly contribute to at least one project. At the end of the experience, the student is expected to competently discuss the hypothesis, the methods used to test the hypothesis, and should have contributed significantly to a manuscript. This is a serious commitment and should be treated as another class with the requirement of outside reading as well as bench top skills. Students unable to maintain a weekly commitment will not be considered for renewed participation in subsequent years.


    NOTE: This researcher is currently not accepting applications for the Undergraduate Research Experience program.

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