Jing Liu

Email Address: jinglius@uic.edu
College: Medicine Department: Surgery
Title: Associate Professor
Office: COMRB 5139 Phone: 7732515389
Webpage: https://cancer.uillinois.edu/member/jing-liu-phd/
Participating in the Chancellor’s Undergraduate Research Awards program: Yes

Research Interest:
The research in our laboratory focuses on the molecular mechanisms that govern inflammation in pulmonary diseases, including lung cancer, COPD, asthma, and ARDS. Inflammation is part of the host defense system against invading pathogens, but deregulated inflammation is also known to play a crucial role in the pathology of various diseases, from inflammatory lung diseases to cancer. The molecular mechanism that controls inflammation and the pathological impact of deregulated inflammation on human diseases are incompletely understood. Our work discovered that the Myc-interacting zinc finger protein 1 (Miz1) plays a central role in signaling the resolution of inflammation through epigenetic regulation of C/EBPd and/or NF-kB activity by histone modifications, with implication in COPD. Additionally, our work uncovers the stress-activated protein kinase JNK2 as a fine tuner of inflammasome through promoting mitophagy, thereby maintaining immune homeostasis.

Minimum time commitment in hours per week:

Qualifications of a Student:

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